Every time I see the awesome work of the Special Effect people it reminds me of the responsibility we have as software engineers: we may be able-bodied but not everybody is, it's up to us to make our software accessible to as many users as possible.
And yet we build websites that break when someone tries to increase the text size. That's plain wrong. Machines must adapt to people, not the other way around.
Octodon is a nice general purpose instance.